Entries Tagged as 'Treatment'

Atrial Fibrillation Ablations Fail From Sleep Apnea

Atrial fibrillation is very common in those with obstructive sleep apnea, and up to half of those who have afib also have sleep apnea. However, few studies have looked at the impact of sleep apnea on the success of catheter ablation and whether sleep apnea treatment with a continuous positive airway pressure (CPAP) machine makes a difference in arrhythmia recurrence.

A new study shows that severe obstructive sleep apnea is a powerful predictor of atrial fibrillation ablation failure and suggests the need for early diagnosis and treatment of sleep apnea in those with atrial fibrillation.

Read more:  Severe Obstructive Sleep Apnea Predicts Atrial Fibrillation Ablation Failure, New Study Says

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Improved Quality of Life From Cryoballoon Ablation for Atrial Fibrillation in the STOP AF Study — Findings Reported at Heart Rhythm 2010 and Cardiostim 2010

At Heart Rhythm 2010, there was an update on the results of the STOP AF (Sustained Treatment of Paroxysmal Atrial Fibrillation) clinical trial that involved patients who received cryoablation using the Arctic Front® Cardiac CryoAblation Catheter System. At twelve months following these procedures, these younger, highly-symptomatic patients had better quality of life and dramatically decreased afib symptoms.

In the article linked below, Jeremy Ruskin, MD, chair of the STOP AF trial steering committee and Director of the Cardiac Arrhythmia Service at Massachusetts General Hospital, discusses those results along with some of the technical advantages of the cryoballoon catheter. We also report on data just released at Cardiostim 2010 regarding shorter procedure times with this catheter.

Read more:  STOP AF Cryoablation for Atrial Fibrillation — Quality of Life Results and Technical Considerations

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Discussions at Heart Rhythm Society on Whether Catheter Ablation Can Successfully Treat Persistent and Longstanding Persistent Atrial Fibrillation

Catheter ablation in persistent and longstanding persistent atrial fibrillation patients has traditionally had low success rates since many of the triggers causing atrial fibrillation are dispersed throughout the left atrium. Thus isolation of the pulmonary veins, which works well for those with paroxysmal atrial fibrillation, is often an incomplete solution for those with persistent forms of afib.

At Heart Rhythm Society 2010, Dr. Christopher Cole looked at differing pulmonary vein isolation ablation strategies for different kinds of patients and discussed an analysis into success rates with various ablation techniques for those with persistent and longstanding persistent afib, including complex fractionated arterial electrograms (CFAE).

Learn more about catheter ablation options and success rates for persistent and longstanding persistent afib here:

Can Catheter Ablation Successfully Treat Persistent Atrial Fibrillation

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If Catheter Ablation Reduces Alzheimer’s Disease and Stroke Risk Then Keeping Atrial Fibrillation Patients in Sinus Rhythm May Become the Goal

Findings presented at Heart Rhythm 2010 showed that stopping atrial fibrillation—whether through medication, surgery, or in the case of this study, catheter ablation— could potentially prevent the risk of developing Alzheimer’s disease and other dementias and also reduce the risk of stroke and death.

Doctors John D. Day, MD, and T. Jared Bunch, MD, at Intermountain Medical Center in Salt Lake City, Utah, showed that successfully treating atrial fibrillation by catheter ablation could significantly reduce Alzheimer’s disease and strokes. If this is proven out in other studies, this could potentially change the treatment practices for atrial fibrillation patients such that staying in sinus rhythm becomes the goal. Read more at:

Stopping Atrial Fibrillation Could Reduce the Risk of Stroke and Alzheimer’s Disease — 6-10-10

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Washington Post looks at how “atrial fibrillation is easy to find, but evidence on how best to treat it isn’t”

Atrial fibrillation took center stage in a feature story in Tuesday’s Washington Post. The article not only looked at treatment for atrial fibrillation, but also at what afib does to patients. The atrial fibrillation experiences of Mellanie True Hills, founder of StopAfib.org, were included in this story.

Read more at:

Washington Post Highlights Afib: Atrial fibrillation is easy to find, but evidence on how best to treat it isn’t

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What Factors Can Predict Atrial Fibrillation Catheter Ablation Success

Doctors are trying to identify the characteristics that predict which patients aren’t likely to be successful with a catheter ablation for their atrial fibrillation. At a session at the recent Heart Rhythm Society annual meeting, some of the factors discussed included left atrial size, left atrial volume, left ventricle dysfunction (improper functioning of the left ventricle), time spent in afib, and extensive atrial fibrosis.

Read more:  Predictors of Atrial Fibrillation Catheter Ablation Success — Presentations from Heart Rhythm Society — 6/4/10

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What is Success for Atrial Fibrillation Catheter Ablation — Report from Heart Rhythm Society 2010

An important session at Heart Rhythm Society 2010 was “Medical Issues After Ablation for Atrial Fibrillation and Flutter.” It dealt with what constitutes success following catheter ablation for atrial fibrillation (afib) and atrial flutter, and which is more important, the medical definition or the patient’s definition.

Which definition is used can have implications for treatment following catheter ablation. This session explored those issues, including the blanking period, repeat ablations, monitoring for asymptomatic events, and anticoagulation to deal with stroke risk.

Read:  What is Catheter Ablation Success and What are the Implications

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Dr. Nassir Marrouche Discusses Use of MRI to Personalize Atrial Fibrillation Treatment and Avoid Stroke – Video

In this video interview, Dr. Nassir Marrouche, Executive Director of the Comprehensive Arrhythmia Research and Management (CARMA) Center at the University of Utah Health System, discusses the findings he recently presented at the Heart Rhythm Society annual meeting in Denver. He discussed the intriguing way they are using MRI (magnetic resonance imaging), to personalize atrial fibrillation (AF) treatment by determining the degree of atrial fibrosis in the atrium to determine whether catheter ablation is likely to work. Since the extent of atrial fibrosis also correlates with stroke risk, this “staging” approach also can dictate whether anticoagulation is needed following the procedure.

The effectiveness of this Utah AF staging system will be tested through a multicenter clinical trial involving Cleveland Clinic, Mayo Clinic, the University of Pennsylvania, Loyola, CHU Bordeaux, and a number of other centers around the world.

Watch the video:

Interview with Dr. Nassir Marrouche on Personalized Atrial Fibrillation Treatment Through “Staging”

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African Americans Show Less Risk of Atrial Fibrillation and Women Need More Aggressive Afib Treatment — Findings from HRS

At Heart Rhythm 2010 in Denver recently, a session on demographic factors influencing atrial fibrillation management and outcomes featured the following research findings:

  • African Americans Have Less Risk Than Caucasians of Atrial Fibrillation After Bypass Surgery
  • Blacks Have Lower Risk of Atrial Fibrillation After Age 60 Than Whites Despite Higher Risk Factors
  • Women with Atrial Fibrillation May Need More Aggressive Anticoagulation Than Men to Avoid Stroke
  • Women with Atrial Fibrillation Are Referred Less Often to AF Centers and Are Less Likely to Receive Aggressive Treatments

Read about these research findings at: Race and Gender Issues Influencing Atrial Fibrillation Management — News from Heart Rhythm 2010

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Use of MRI to Personalize Atrial Fibrillation Treatment and Avoid Stroke – Presentation by Dr. Nassir Marrouche at HRS

At Heart Rhythm Society 2010, we saw intriguing new research into personalized afib treatment and stroke prevention that was presented by Dr. Nassir Marrouche and Dr. Marcos Daccarett of the Comprehensive Arrhythmia Research and Management (CARMA) Center at the University of Utah Health System.

They have developed a way, using MRI (magnetic resonance imaging), to personalize atrial fibrillation (AF) treatment by “staging”, which determines whether catheter ablation will likely stop the afib based on the degree of fibrosis in the atrium. The extent of atrial fibrosis also was found to correlate with stroke risk. The stage indicates appropriate catheter ablation treatment and whether anticoagulation is needed following the procedure. The researchers indicated that the best results come from intervening early into atrial fibrillation.

To further validate the effectiveness of the Utah AF staging system, they have initiated a multi-center clinical trial that will involve a number of centers worldwide, including Cleveland Clinic, Mayo Clinic, Loyola, the University of Pennsylvania, and CHU Bordeaux.

Read more:  Personalized Atrial Fibrillation Treatment Using New Method to “Stage” AF

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